Compile Data Set for Download or QSAR
Found 460 of ic50 data for polymerid = 50001795,50006440
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM356235(BDBM50441572 | US10485800, Example 1 | US9814704, ...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human MLK3 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W380MTPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human MLK3 using MBP as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5KB8PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441571(CHEMBL2436982 | US10485800, Example 18 | US9814704...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50458548(CHEMBL4218417)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant GST-tagged full length human MLK3 KD expressed in baculovirus using myelin basic protein as substrate preincubated for 15 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441570(CHEMBL2436976 | US10485800, Example 17 | US9814704...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50108295(CHEMBL288817 | Indolocarbazole analogue)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571B94PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50108296(CHEMBL289772 | Indolocarbazole analogue)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571B94PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50108293(CHEMBL277817 | Indolocarbazole analogue)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571B94PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM14186(12,13-Dihydro-6H,14H-naphthyl[3,4-a]pyrrolo[3,4-c]...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2MJXPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2MJXPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441569(CHEMBL2436981 | US10485800, Example 4 | US9814704,...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50058332(CHEMBL299496 | methyl 10,23-di(ethylsulfanylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of flag-tagged MLK3 (unknown origin) expressed in human HeLa cells assessed as reduction in enzyme autophosphorylation incubated for 20 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9DG3PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441566(CHEMBL2436977 | US10485800, Example 179)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50108299(CHEMBL288229 | Indolocarbazole analogue)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571B94PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM14174(12,13-Dihydro-5H,6H,14H-naphthy[3,4-a]pyrrolo[3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2MJXPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant GST-tagged full length human MLK3 KD expressed in baculovirus using myelin basic protein as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G163G3PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571B94PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM14179(3-thia-13,23-diazahexacyclo[14.7.0.0^{2,10}.0^{4,9...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2MJXPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50108297(CHEMBL288816 | Indolocarbazole analogue)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571B94PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of MLK3 (unknown origin) by NanoBRET cellular target engagement assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD22MPPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM14177(3,13-diazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2MJXPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441573(CHEMBL2436979 | US10485800, Example 40 | US9814704...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50108291(CHEMBL36891 | Indolocarbazole analogue)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571B94PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM2581(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2MJXPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50419254(CHEMBL1835063)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of human MLK3 using myelin basic protein as substrate in presence of [gamma-33P]-ATP by hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8XG3PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM24947(3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[...)copy SMILEScopy InChI
Affinity DataIC50: 55nMpH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8K09PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50108292(CHEMBL37529 | Indolocarbazole analogue)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571B94PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM14188(3-thia-13,23-diazahexacyclo[14.7.0.0^{2,10}.0^{4,9...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2MJXPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM24942(CEP-1347 | CHEMBL290352 | methyl (15S,16R,18R)-10,...)copy SMILEScopy InChI
Affinity DataIC50: 64nMpH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8K09PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM24949(3-(2-hydroxyethyl)-20-(propan-2-yloxy)-3,13-diazah...)copy SMILEScopy InChI
Affinity DataIC50: 65nMpH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8K09PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441568(CHEMBL2436983 | US10485800, Example 9 | US9814704,...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibition of MLK3 (unknown origin) after 20 mins by scintillation counting analysis in presence of [33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P270KSPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM24948(3-(3-hydroxypropyl)-20-methoxy-3,13-diazahexacyclo...)copy SMILEScopy InChI
Affinity DataIC50: 87nMpH: 7.2 T: 2°CAssay Description:The MLK kinase assays were performed by using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. The inhibition curves were genera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8K09PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM14173(3,13-diazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:The MLK1, MLK2, and MLK3 assays were performed using the Millipore multiscreen trichloroacetic acid (TCA) in-plate format. IC50 values were calculate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HT2MJXPubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50108294(CHEMBL288818 | Indolocarbazole analogue)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2571B94PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM420237(US10485800, Cmpd ID HA | US10485800, Example 204)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B91DWUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM420238(US10485800, Cmpd ID HB | US10485800, Example 205)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B91DWUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM420240(US10485800, Cmpd ID Preparation of 1-(4-(4-(3-(1H-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B91DWUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM420241(US10485800, Cmpd ID 5-(4-((3,4-dimethylpiperazin-1...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B91DWUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM420242(US10485800, Cmpd ID Preparation of 5-(4-((1H-imida...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B91DWUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM420243(US10485800, Cmpd ID FW | US10485800, Example 177)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B91DWUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441566(CHEMBL2436977 | US10485800, Example 179)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B91DWUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM420245(US10485800, Cmpd ID FZ | US10485800, Example 180)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B91DWUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50441567(CHEMBL2436978 | US10485800, Example 181)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B91DWUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM464084(US10787436, Compound I-20)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3P6JUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3P6JUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM464110(US10787436, Compound I-53)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro kinase assays with immunoprecipitated proteins (or recombinant CAK complexes) were performed as follows. Kinase reactions were performed in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3P6JUS Patent
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Califia Bio Inc.

Curated by ChEMBL
LigandPNGBDBM354888(Preparation of N-methyl-4-{5-[4-(4-methyl-piperazi...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1MRNUS Patent
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